This study reports findings from four experiments investigating the interpretive patterns of Mandarin reflexive ziji by Mandarin native speakers and L2 learners of Mandarin whose L1s were English, Italian, Japanese, or Korean. Since the non-local interpretation to a large extent was modulated by discourse contexts and as predicted by the Interface Hypothesis, linguistic properties involving the syntax-discourse interface conditions pose more difficulties for L2 learners, the results of the long-distance binding condition showed that L2 learners performed non-target-like even at the advanced proficiency level, especially for learners whose L1s do not exhibit this property. For subject-orientation, previous accounts mainly considered it as the property to do with syntactic parameter setting, and our results demonstrated that L2 learners with advanced level of proficiency and have enough exposure to the target L2 were able to reach the target-like level of performance. Furthermore, our results also demonstrated that a default pattern (i.e., the English type of pattern for locally bound reflexives which allow both the subject and the object as the antecedents) showing the effect of the locality constraint and allowing both the subject and object NPs as the antecedent for ziji existed at the early stage of L2 acquisition, even for L2 learners whose L1s manifest the properties of long-distance interpretation and subject-orientation.