Nanoceramic waste material used in interlocking brick manufacturing not only provides a promising resource to produce a high-quality brick, but also helps to properly encounter the problem of waste disposal. It is a good option for use in mortar and concrete because waste ground ceramic has a highly resistant structure and cannot be processed by any recycling system and because it is produced in large quantities. Thus, this study focused on two different phases: in the first phase, the use of nanoceramic as a pozzolan in mortar as interlocking brick was investigated. The application of 5, 10, 15, 20, 25, and 30% nanoceramic powder replaced with cement by weight. In all cases, compressive strength, density, water absorption, effloresce, thermal conductivity, and elevated temperature tests were performed. The results show that adding nanoceramic powder up to 10% does not have a significant effect on the compressive strength of brick. But 15–30% nanoceramic powder provides excellent compressive strength and resistance to all other tests. Furthermore, using any amount of nanoceramic powder in the mortar reduces its water absorption capacity. In addition, using because of silica content available in nanoceramic powder and pozzolan simultaneously leads to improved compressive strength and a reduced water absorption capacity and other effects on tests.