Leukopenia in ICU

Leukopenia, characterized by a reduction in white blood cells, is a significant marker in intensive care units (ICUs) for predicting increased infection risks and adverse outcomes. This chapter delves into leukopenia, with a focus on neutropenia—a condition marked by decreased neutrophils, crucial for infection defense. Through comprehensive analysis, including etiology, classification, pathophysiology, and management strategies, this chapter offers invaluable insights for ICU practitioners. It emphasizes the importance of early identification, understanding underlying causes, and employing targeted treatments to mitigate complications, highlighting the role of granulocyte colony-stimulating factor (G-CSF) and infection control measures. The chapter aims to enhance patient care by providing a detailed guide on managing leukopenia and neutropenia in critically ill patients.