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Candidiasis, Drug Resistance, and Translational Research

  • Anubhuti Jha,
  • Awanish Kumar

摘要

Candida albicans is a yeast occurring naturally in the human body and causes a disease candidiasis in immunocompromised person. This pathogen has ideal living and breeding conditions in a healthy person and assembled in susceptible due to an optimum habitat. This cycle of infection must be understood in order to understand how infections of C. albicans might arise in human. The understanding and interruption of occurrence of the disease would be helpful to prevent and control candidiasis. This chapter of the book helps to understand these factors. It discusses the introductory details of C. albicans and candidiasis, facts of its pathogenicity mechanisms like white-opaque cellular switching, filamentation, formation of biofilm, and antifungal resistance. Information on translation research has been also provided.