Selective Detection of Melamine Using Misaligned Fiber Interferometer

The integration of fiber optic interferometry with molecular imprinting polymer (MIP) can be a substantial way to construct a compact, fast, stable, selective, and precise biosensor. Here in this work, we have fabricated a sensor using a misaligned fiber structure through functionalizing with MIP nanoparticles for accurate detection of harmful food-adulterant melamine. The sensor provides an operating range of 10–6 to 10–2 M concentration of melamine with maximum sensitivity of 39.16 × 106 pm/M with a minimum detection limit of 1.53  \(\upmu\) M. This combined approach is potentially suitable for the fabrication of compact, fast, cost-effective, biosensors for remote biosensing operations.