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Drug Delivery via Lipid-Based Nanocarriers

  • Deepa Suhag,
  • Swati Kaushik,
  • Vinod Bala Taxak

摘要

Drug delivery using lipid-based nanocarriers has emerged as a promising approach to overcome various challenges associated with conventional drug delivery systems. Lipid-based nanocarriers offer a versatile platform for encapsulating a wide range of drugs, including hydrophobic and hydrophilic compounds, peptides, and nucleic acids. Their unique structural properties, such as biocompatibility, biodegradability, and ability to mimic biological membranes, make them ideal candidates for targeted and controlled drug delivery. The importance of drug delivery via lipid-based nanocarriers is underscored by their ability to enhance drug bioavailability, improve therapeutic efficacy, and reduce systemic toxicity. By encapsulating drugs within lipid matrices, nanocarriers protect them from degradation, prolong circulation time, and facilitate targeted delivery to specific tissues or cells, thereby minimizing off-target effects and maximizing therapeutic outcomes. Lipid-based nanocarriers offer a versatile platform for co-delivery of multiple drugs or combination therapies, enabling synergistic effects and overcoming drug resistance. Their tunable physicochemical properties allow for customization of drug release profiles, enabling sustained or triggered release kinetics tailored to specific therapeutic needs. Drug delivery via lipid-based nanocarriers holds immense potential for revolutionizing the field of therapeutics by addressing current limitations and facilitating the development of more effective and personalized treatment strategies.