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Epidemiology, Risk Factors and Histopathological Profile of Prostate Cancer

  • Mehrdad Hashemi,
  • Farnaz Azizi,
  • Niloofar AbolfathyNajmabady,
  • Samira Moradi,
  • Munes Ghorbanalinia,
  • Sima Orouei,
  • Behdokht Jamali,
  • Rasoul Raesi,
  • Faramarz Khosravi,
  • Maliheh Entezari,
  • Mina Alimohammadi,
  • Kiavash Hushmandi,
  • Mitra Behroozaghdam

摘要

An estimated 366,000 men lose their lives to prostate cancer every year, while an additional 1.6 million men receive a prostate cancer diagnosis. The current level of evidence regarding several dietary, lifestyle, and genetic variables linked to the risk of prostate cancer is reviewed in this review. Among male cancers, prostate cancer ranks second in incidence and fifth in mortality rates globally. Early stages of prostate cancer may not cause any symptoms at all, and the disease tends to progress slowly, so regular monitoring may be all that’s needed to catch it early. There is a substantial correlation between age and prostate cancer incidence and fatality rates, with the greatest incidence observed in males aged 65 and up. When compared to white men, African-American men experience a higher incidence rate and a more aggressive form of prostate cancer. A lower risk of prostate cancer can be achieved by reducing consumption of high-fat meals, increasing consumption of vegetables and fruits, and increasing exercise, yet there is currently no data on how to prevent this disease. African-American men and men with a family history of the disease should undergo screening at the age of 45.