Synthesis and Biological Evaluation of Thiophene and Its Derivatives

Sulfur-containing heterocycles are ever-trending core molecules in pharmaceutical research. Derivatives of thiophene are a class of S-containing heterocycles that have been long known for their biological activities. They are important analogs for medicinal chemists because a large number of advanced compounds with a varied range of biological activities can be developed from them. In this chapter, information on various latest methods for the synthesis of thiophenes and their derivatives is compiled along with their biological evaluations. This chapter will be helpful for researchers and academicians working in the field of S-containing heterocycles.