Hemophilic Pseudotumor

Hemophilia is a hereditary disease caused by a deficiency of coagulation factors VIII or IX. Hemophilic pseudotumor is a rare but serious complication of hemophilia, which often occurs in femur, pelvis, iliac bone, and other parts of the body, but rare in skull and jawbone [1–7]. Its main clinical manifestations are repeated bleeding in extra-articular bone or soft tissue, resulting in intra-articular blood accumulation, and the continuous enlargement of the capsule cavity to compress and destroy the adjacent tissues; patients usually have no obvious symptoms in the early stage, but after the involvement of the adjacent tissues, specific symptoms appear. The clinical diagnosis is based on the history of traumatic bleeding and X-ray, ultrasonography, CT, and MRI examinations. Treatment includes factor replacement therapy, radiotherapy, and surgery (including local suction/drainage, surgical resection, and amputation).