Familial Gigantiform Cementoma

Familial gigantiform cementoma (FGC) is a rare autosomal dominant genetic disease and a benign proliferative lesion of cementum. The disease is easy to occur in teenagers, and the lesions progress rapidly in adolescence but tend to stagnate at the end of adolescence. Bone swelling growth above FGC and multiple quadrants of the mandible are the main manifestations, and the anterior part of the mandible is the area that occurs frequently, usually appearing with evident occlusal disorder and facial deformity, seriously affecting the maxillofacial shape and oral function [1–4]. In addition, it is often accompanied by systemic manifestations, such as long bone fractures of limbs, etc. [3–5]. Diagnosis should be combined with clinical manifestations, imaging features and pathological features. FGC recommends operation, and the operation must be thorough. Incomplete lesion resection will lead to the accelerated growth of residual lesions. For bone defects formed after resection, a fibula flap is often used for reconstruction and repair.