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Microbiome-Based Therapies for Mental Health Disorders

  • Quratulain Maqsood,
  • Mariam Aman,
  • Nazim Hussain,
  • Muhammad Zafar Saleem,
  • Muhammada Mahnoor

摘要

The symbiotic relationship between the human gastrointestinal tract and microbial communities plays a vital role in maintaining overall bodily homeostasis and defending against diseases. This link to the brain emphasizes the significant influence of the gut microbiota on mental well-being. The significance of microbial dysbiosis in the genesis of disease, particularly in mental health problems, has been clarified by research on the gut microbiome. This chapter investigates how the gut-brain axis affects behavior and brain function in relation to the gut microbiota. It looks into microbiome-based treatments for mental health, such as dietary changes, fecal microbiota transplantation, probiotics, and prebiotics. An overview of the available data on the effectiveness, security, and processes of various interventions is given in this chapter. The difficulties and possibilities of using microbiome-based treatments in clinical settings are also covered. Ultimately, the chapter concludes by considering the potential impact of these emerging therapies on the treatment of mental health disorders. By offering a comprehensive review of microbiome-based therapies for mental health, this chapter provides valuable insights into this rapidly evolving field.