Multiscale Studies for Estimation of Elastic Properties of B. mori Silk

Bombyx mori silk has emerged as a dependable biomaterial in bone tissue engineering. B. mori silk fibroin, when combined with hydroxyapatite (HAP, a mineral in human bone), is a suitable implant material for bone and tissue engineering. The mechanical properties (tensile strength, elastic modulus, etc.) and behavior during deformation under tensile loading on a continuum scale are essential for designing silk-based bone grafts and tissue scaffolds. The current study focuses on estimating the mechanical properties of B. mori silk through numerical modeling at the macrolevel. Also, the correlation of properties at the nanoscale and macroscale is important to analyze the overall deformation characteristics of the material. Hence in this investigation, we will also see the correlation of the properties to get a better overview of the deformation characteristics.