Litchi (Litchi chinensis), Salak, and Strawberry Seeds in Producing Antiproliferation

Fruits high in polyphenols are thought to be nutritious for people. Traditional Medicines (TMs) made from fruit are abundant in polyphenols, have anti-inflammatory and antioxidant properties, and have been experimentally shown to be effective in treating some chronic illnesses, including cancer. The litchi seed, one of the traditional remedies for pain relief and sweating, has been found to have high levels of polyphenolic species, including flavonoids and proanthocyanidins, and to exhibit strong antioxidant activity. The anti-tumour properties of the various litchi parts are discussed in-depth, which also emphasises the key biochemical mechanisms at play. Snake fruit (Salacca zalacca) is a distinctive tropical palm that produces drupes, which are fruits with skin that mimicking snake scales and is leathery and scaly. Due to its abundance of antioxidants, phenolics, vitamins, and minerals, numerous studies have shown that the nutritional profile of this fruit is similar to that of more well-known fruits like mango, kiwi, and apple. Despite having enormous food and health advantages, snake fruit is still underused and unheard of on the international market. Gallic acid, quercetin, chlorogenic acid, epicatechin, proanthocyanidins, lycopene, and beta-carotene are just a few of the volatile and aromatic chemicals that have been found in this fruit as a result of the phytochemical analysis. Pharmacological research on the fruit’s flesh and skin has revealed amazing anti-inflammatory, anti-cancer, antioxidant, and anti-diabetic properties. This chapter offers details on Salacca zalacca’s botanical makeup as well as scientific research on the plant’s various pharmacological and phytochemical advantages. This might aid in highlighting the information gaps and lack of study on this plant. Although strawberries contain a wide variety of phytochemicals, the biological actions and underlying molecular mechanisms are still inadequately understood. The antioxidant, anti-inflammatory, and antiproliferative potentials of strawberry extract against various cancer cells were reported. The Maehyang cultivar’s strawberry extracts displayed 1,1-diphenyl-2-picrylhydrazyl free radical rescue abilities. Additionally, strawberry extracts reduced the development of cancerous cells from the human stomach (SNU-638) and fibrosarcoma (HT-1080), lung (A549), colon (HCT-116), and lung (A549). It is hoped that the information offered in this chapter will make a substantial contribution to the research that is currently being conducted on the many different kinds of seeds.