Periapical Pathosis
摘要
Numerous sequelae may follow untreated pulp necrosis. These are dependent on the virulence of the microorganisms involved and the integrity of the patient’s overall defense mechanisms. From its origin in the pulp, the inflammatory process extends into the periapical tissues, where it may present as a granuloma or cyst (if chronic) or an abscess (if acute). Acute exacerbation of a chronic lesion may also be seen. The necrotic pulpal tissue debris, inflammatory cells, and bacteria, particularly anaerobes, all serve to stimulate and sustain the periapical inflammatory process.