Stomach: VS Classification/MESDA-G

The VS classification system developed by the author (Kenshi Yao) [1] is the most widely accepted diagnostic system for magnifying narrowband imaging (M-NBI) of the stomach [2]. The VS classification system employs anatomical terms as endoscopic markers for analysis. Anatomical components visualized using M-NBI were divided into microvascular (MV) and microsurface (MS) patterns. As shown in ◘ Fig. 1a–c, the subepithelial capillary and collecting venule were visualized for MV pattern, while the marginal crypt epithelium (MCE), crypt opening (CO), and intervening part (IP) between the crypts were identified for the MS pattern. In addition, in terms of the pathological status, the light blue crest [3] and white opaque substance [4] can be markers for microsurface patterns.