Esophagus: The BING Classification

Barrett’s esophagus (BE) is a metaplastic alteration of the normal esophagus epithelium, predisposing to the development of esophageal adenocarcinoma (EAC), of which the 5-year overall survival rate is a dismal 17% [1, 2]. International guidelines have recommended endoscopic surveillance for patients with BE to detect early dysplasia [3, 4]. Endoscopic surveillance is typically performed with high-definition white light imaging (WLI) with quadrantic biopsies taken as per the Seattle protocol [5]. However, early Barrett’s dysplasia are easily missed due to subtle mucosal change [6, 7].