Application of Peptides for the Treatment of Diabetes: A Plant-Based Bioactive Material

The advent of analytical methodologies for efficacy assessment, identification, and measurement has forged novel pathways for the exploration of plant-derived therapeutic agents. Within the realm of protein and peptide analysis, these methodologies have markedly enhanced the generation of evidence-based conclusions. Bioactive peptides, scrutinized for their therapeutic potential across diverse ailments, are engendered through enzymatic hydrolysis of parent plant proteins. Peptides exhibit considerable pharmacological attributes such as antimicrobial, antioxidant, anti-inflammatory, immunomodulatory, antidiabetic properties, and efficacy in mitigating neuropathic pain. This review will encompass the delineation of plant-derived bioactive proteins and peptides alongside in vitro and in vivo findings pertinent to diabetes treatment. The pharmaceutical sector confronts hurdles in the extraction, isolation, characterization, and commercial exploitation of plant proteins due to the presence of numerous secondary metabolites that impede their functionality. The realm of peptide drugs targeting diabetes is experiencing rapid expansion, and the exploration of plant-derived bioactive peptides holds promise for unlocking potential avenues for the management of various maladies on both scientific and financial fronts.