The number 108 is often considered special because of its place in certain religious and mythological traditions. The number 108 is considered auspicious in Hinduism, Sikhism, Buddhism, and Jainism. In addition to many other amazements of 108, geometrical properties and astronomical coincidences are worth noting. What is so interesting about 108? The number 108 is the smallest number whose divisors (i.e. 1, 2, 3, 4, 6, 9, 12, 18, 27, 36, 54, and 108) contain every digit at least once and is also the smallest number that can be partitioned into six distinct primes such that the sum of any five is prime. Such fascinating observations, along with many amazing coincidences like ‘108 Emergency Ambulance Service in India’, are discussed in this chapter.