Integrated High-Throughput Omics Approaches in Production of Natural Products in Plant

To fully understand the vast biological complexity that exists within cells, omics studies must be conducted. And the data obtained from these omics platforms needs to be validated in order to reach the final conclusion. This multi-omics data largely exhibits the data generated from genome, transcriptome, proteome, metabolome, and epigenome. Integration of multi-omics approaches appears to be more promising in understanding complicated biology systematically and comprehensively. The production of vast amounts of omics data and the development of computational bioinformatics have made it much easier to integrate these two potent tools to elucidate the functional application for recognizing the molecular interactions taking place within the cell. Multi-omics approach leads to the finding of the associated biological network pathways and the genes responsible for the production of natural products within plants. With the advancement of the high-end instrumentation like sequencing technology, mass spectrometry, and controlled phenotyping facility, it is more informative to gain the proper function of the gene and its interaction with the environmental signals. In this chapter, a brief overview on broad omics approaches and the ways for associating the multi-omics data to draw out the functions of various genes involved in the production of natural compounds within the plants are mentioned.