The objective of this chapter is to understand the ecosystem of the FinTech sector in Africa and the Middle East and to present the success stories of the FinTech players who have contributed or are contributing to the development. The chapter presents a comprehensive vision of the FinTech ecosystem and the necessary contributors as well as the main strategies and policies implemented by the leaders in the region. Despite the divergence in terms of the level of development and investment, there are socio-demographic similarities linked mainly to the large percentage of young population in the region which explains the development of the sector. The leading countries have created a promising framework through complementary; digital economy strategy, AI strategy, and cybersecurity strategy. The chapter delves into the dynamic that exists in the region in terms of civil society and training offer. We note that, despite the difficult development in some countries, the FinTech sector represents a niche with promising socio-economic potential.