Developing sustainable health systems has become essential in an era of growing health issues and environmental changes. This chapter explores how the sustainable health system should be shaped among labour dynamics, environmental sustainability, primary healthcare, and alternative finance strategies. We suggest that developing resilient health systems that can adapt to the dynamic needs of communities requires a comprehensive strategy. Primary healthcare that promotes cost and accessibility, leading to universal health coverage, may also aid in the development of sustainable healthcare systems. We emphasize practices in incorporating environmental issues into healthcare services, increasing worker capacity, and organizing health revenue and expenditure, using case examples from different countries. The chapter ends with suggestions for governments’ strategies that address the multifaceted nature of health system sustainability by referring to the example countries.