Supramolecular self-assembled aggregation-induced emission (AIE)-active materials have received considerable attention in many areas of chemistry, biology, medicine, bioimaging, sensing, catalysis, environment, and materials science. Due to their robust light-harvesting ability, efficient energy/electron transfer, photostability, and effective separation of photoexcited carriers, AIE active materials have become highly promising candidates for photocatalysis. It has been proved that tailored aggregation-induced emission materials can be harnessed to directly perform efficient heterogeneous catalytic organic reactions and function both as an oxidizing and a reducing agent upon activation. Enhancing the photocatalytic efficiency of organic photocatalysts has remained a long-standing challenge for the researchers. The work presented here provides an overview of most representative examples of AIE-active materials with applications in photocatalytic reactions. Given the significance of the subject, in this book chapter, we seek to delve into the mechanistic aspects of the photocatalysts and expound upon their various applications. This will help in guiding the development of AIE-based high performance, and stable and durable photosensitizers with exciting architectures and functions.