Facile Green Synthesis of Silver Nanoparticles Using Passiflora edulis and Its Efficacy Against the Breast Cancer Cell Line

The field of plant-mediated nanoparticle synthesis is growing rapidly worldwide. It has been revealed that plant biomolecules are useful in the production of stable, convenient, and non-toxic silver nanoparticles (AgNPs). In this study, a biosynthetic method employing Passiflora edulis leaf extract as a reducing and stabilizing agent was used to synthesis environmentally acceptable AgNPs. X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and dynamic light scattering (DLS) were among the characterization methods used on the synthesized AgNPs. The ethanol extract from Passiflora edulis, which showed an absorption peak at 328 nm and the synthesized of AgNPs as indicated by the UV-visible spectra. The produced AgNPs were shown to be crystalline in the XRD pattern; however, the SEM images primarily showed spherical forms. AgNPs were shown to be capped by bioactive compounds synthesized from AgNPs in the FT-IR investigation. Additionally, the produced AgNPs demonstrated antibacterial efficacy against Klebsiella, Staphylococcus aureus, and Escherichia coli. The growth of various bacterial strains was likewise suppressed by the ethanol extracts of P. edulis via AgNPs. Furthermore, the synthesized silver nanoparticles were evaluated for their possible anticancer functioning against breast cancer cells. Our results demonstrate that AgNPs produced biologically cause cell death by controlling cell division and promoting nuclear disintegration.