Agrobacterium rhizogenes-Mediated Genetic Transformation: A Potential Approach to Enhance the Antiallergic Potential of Medicinal Plants by Endorsing the Production of Responsible Phytochemicals

Allergic disorders are a global health issue that requires creative development to produce successful therapeutic outcomes. Medicinal plants have shown potential in allergy mitigation due to their vast array of bioactive chemicals. This book chapter discusses the novel use of Agrobacterium rhizogenes-mediated genetic transformation as a possible technique for enhancing medicinal plants’ antiallergic potential. By causing the growth of hairy roots in the host plant, A. rhizogenes, a soil-borne bacterium, provides a unique platform for genetic transformation. This method enables the steady integration of foreign genes and, as a result, the creation of bioactive substances. The chapter investigates the mechanisms underpinning A. rhizogenes-mediated genetic transformation and its potential to influence the production of phytochemicals with antiallergic effects. Researchers can adjust the plant’s metabolic pathways to optimize the production of medicinal substances by regulating the expression of key genes involved in the biosynthesis of antiallergic phytochemicals. Finally, this chapter finishes with insights into the revolutionary approach’s future directions, emphasizing its potential to revolutionize the development of allergy-alleviating medicinal plants. This chapter is a valuable resource for plant biotechnology, pharmacology, and allergology researchers, academics, and professionals, providing a comprehensive understanding of A. rhizogenes-mediated genetic transformation as a powerful tool for enhancing the antiallergic potential of medicinal plants.