Modified Technique “Modus Spirdonov 1” in Fine-Needle Aspiration Biopsy Under Ultrasonographical Control

Fine-needle aspiration biopsy (FNAB) is one of the most used techniques for obtaining cytological material for further evaluation. The authors have developed a different technique in order to obtain a larger amount of biopsy material. Methods: Over a period of 6 years (2016–2022) more than 900 FNABs of mammary glands under US control and local anesthesia were performed at University Hospital “Queen Joanna – ISUL”, Medical University of Sofia, Bulgaria with a new developed hybrid technique – “Modus Spirdonov 1”. In order to statistically confirm the superiority of the team conducted an experiment. For the purpose of the experiment porcine liver and longissimus dorsi muscle were selected as target tissues sampled by standard method with direct grip (n = 60), by using CAMECO syringe pistol (n = 60) and by applying the new modified technique “Modus Spirdonov 1” (n = 60). A comparative analysis of the weight of the samples was performed. Results: The processed results show that the amount of biological material taken with FNAB “Modus Spirdonov 1” weighs 5.53 times more, which is equivalent to an increase of 452.7%. The modified method “Modus Spirdonov 1” significantly exceeds the other two techniques (p < 0,001) according to the quantity of the obtained material. The gathered material is visually significantly richer, including ductal epithelial complexes, abundance of stromal cells, calcifications, detritus, giant cells and macrophages. Conclusion: The described modified technique is a viable alternative to the currently used FNAB and could increase the diagnostic value of the preoperative biopsy in a number of diseases.