The Application of 4-Hexylresorcinol for Wound Healing

This chapter discusses the potential applications of 4-hexylresorcinol (4HR) in wound healing, angiogenesis, and osteoinduction. 4HR has been shown to improve epithelialization, increase angiogenesis, and stimulate osteogenesis. Its ability to modulate the expression of transcription factors, such as Sp1, E2F, and TGF-β1, contributes to these healing processes. Additionally, 4HR has been found to have anti-inflammatory properties, further supporting its potential as a therapeutic agent. In diabetic animal models, 4HR has demonstrated positive effects on wound healing and vascular network organization. Furthermore, 4HR has shown potential in osteoinduction and dental hard tissue formation, indicating its potential use in bone grafting and dental damage repair. Overall, 4HR holds promise as a candidate for improving wound healing, angiogenesis, and bone and dental regeneration.