Mechanistic Understanding of Inflammation Resolution Using the Atlas of Inflammation Resolution (AIR)

The Atlas of Inflammation Resolution (AIR) is a comprehensive web-based resource that provides a platform for studying inflammation and inflammation resolution. It is designed to capture data on inflammation and its associated pathways to generate new hypotheses on the understanding of processes underlying the resolution of inflammation. AIR has several functions and possibilities. It enables researchers to explore the molecular mechanisms of inflammation and provides a tool for identifying potential therapeutic targets. AIR also allows and facilitates the integration of data from different sources, enabling the development of more comprehensive models of inflammation. This chapter provides an overview of the development, structure, and functionalities of the AIR. Therefore, the reader is guided through the layers and content of the AIR, their construction, the use of plugins for data integration, and various examples of how to use the AIR to generate and investigate own data.