Industrial buildings, especially factories and warehouses, prefer Standing Seam Metal Roofing (SSMR) due to its advantages such as short construction periods and low costs. SSMR is efficient against temperature changes and waterproofing due to the insulation and waterproofing system inserted between the upper and lower panels. However, it is relatively vulnerable to strong winds. Particularly, the installation of SSMR with higher insulation has become more challenging recently, and defects at the Mid-clip due to installer errors have been identified through wind resistance tests. Systems with these defects may not perform optimally against wind and can fail under lower loads. Moreover, it is difficult to detect internal defects after installation due to the structural characteristics of SSMR. In this study, analyses were conducted using finite element models based on the results of wind resistance tests and simple indoor experiments when defects occurred. Ultimately, the study performed a wind resistance evaluation by analyzing the vulnerability based on the defect occurrence rate at the Mid-clip.