Seismic resilience is crucial in Nepal due to its high seismic risk, necessitating a comprehensive evaluation of the seismic performance of typical low-rise and high-rise buildings. This study examines two scenarios: a baseline model with unmodified stiffness and a modified model incorporating stiffness modifiers from regional and international building codes. The research evaluates the impact of these modifiers on structural performance metrics, including base shear, time period, displacement, and drift. Findings highlight the significant role of stiffness modifiers in improving seismic resilience and identify discrepancies between local NBC 105:2020 provisions and international standards. The comparative analysis demonstrates how stiffness modifiers influence the ultimate limit state, revealing increased structural flexibility with lower stiffness modifiers, and differences in response between the equivalent static and response spectrum methods. This study underscores the importance of considering varied stiffness modifiers in seismic design to enhance structural performance and safety.