In the early morning of February 6, 2016, a severe disaster-type earthquake struck Meinong District, Kaohsiung City, Taiwan. This led to the collapse of numerous mid-to-high-rise buildings and resulted in significant casualties. Based on past experiences, the collapse of such buildings during this earthquake was primarily attributed to factors like poor structural system configuration, weak first-story, and torsional effects. To effectively identify and address the aforementioned issues during structural analysis, this study utilized the ‘Taiwan Earthquake Assessment for RC Structures by Dynamic Analysis (TEASDA)’ method. Nonlinear dynamic analysis was conducted using TEASDA method to provide engineers a reference for addressing concerns about inadequate seismic resilience of existing structures. For mid-to-high-rise buildings, their seismic response is complex and characterized by high uncertainty compared to low-rise buildings. Utilizing the current nonlinear static analysis for building seismic assessment may not adequately predict their high-frequency seismic response, potentially yielding non-conservative results. Therefore, the TEASDA method was combined with the structural analysis software ETABS to perform the nonlinear dynamic analysis. In this study, seven sets of earthquake records were employed to perform analyses following general building code requirements. A structural case that after retrofitting was examined to provide insights and reference in conjunction with nonlinear dynamic analysis.