Three-dimensional (3D) printing has transformed biomedical applicationsBiomedical applications, offering precise control over complex structures. Among various biopolymers, cellulose has gained significant attention because of its renewability, biocompatibilityBiocompatibility, and tunable features. Cellulose-based bio-inks exhibit favorable mechanical stabilityMechanical stability and printability, making them good contenders for wound healingWound healing, tissue engineering (TE)Tissue Engineering (TE), and drug delivery. Study aims to explore the improvements in cellulose-based 3D printing3D printing, highlighting its biomedical uses. Recent developments in cellulose-derived bio-inks have enhanced their printability and functional performance. NanocelluloseNano-Cellulose (NC), cellulose derivativesCellulose derivatives, and composite hydrogels have been utilized to fabricate scaffolds with improved biocompatibilityBiocompatibility and mechanical integrity. TE applications have established the potential of cellulose-based constructs in regenerating bone, cartilage, and wound tissues. Additionally, 3D-printed cellulose hydrogels have been explored for drug delivery, enabling sustained as well as targeted release of therapeutics. Boundaries like poor mechanical strength, scalability issues, and complex post-processing techniquesPost-processing techniques hinder widespread adoption despite these advancements. Emerging technologies like 4D printing4D printing and multi-material bioprinting hold promise for overcoming these challenges. Cellulose-based 3D printing3D printing signifies a sustainable and advanced method for application in the biomedical field. Further research on bio-ink formulations, crosslinking strategies, and high-resolution printing techniques is essential to unlock its full potential for clinical and industrial use.

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Cellulose in 3D Printing for the Development of Biomedical Devices

  • Deepak Kumar,
  • Rishabha Malviya,
  • Sonali Sundram,
  • Sathvik Belagodu Sridhar

摘要

Three-dimensional (3D) printing has transformed biomedical applicationsBiomedical applications, offering precise control over complex structures. Among various biopolymers, cellulose has gained significant attention because of its renewability, biocompatibilityBiocompatibility, and tunable features. Cellulose-based bio-inks exhibit favorable mechanical stabilityMechanical stability and printability, making them good contenders for wound healingWound healing, tissue engineering (TE)Tissue Engineering (TE), and drug delivery. Study aims to explore the improvements in cellulose-based 3D printing3D printing, highlighting its biomedical uses. Recent developments in cellulose-derived bio-inks have enhanced their printability and functional performance. NanocelluloseNano-Cellulose (NC), cellulose derivativesCellulose derivatives, and composite hydrogels have been utilized to fabricate scaffolds with improved biocompatibilityBiocompatibility and mechanical integrity. TE applications have established the potential of cellulose-based constructs in regenerating bone, cartilage, and wound tissues. Additionally, 3D-printed cellulose hydrogels have been explored for drug delivery, enabling sustained as well as targeted release of therapeutics. Boundaries like poor mechanical strength, scalability issues, and complex post-processing techniquesPost-processing techniques hinder widespread adoption despite these advancements. Emerging technologies like 4D printing4D printing and multi-material bioprinting hold promise for overcoming these challenges. Cellulose-based 3D printing3D printing signifies a sustainable and advanced method for application in the biomedical field. Further research on bio-ink formulations, crosslinking strategies, and high-resolution printing techniques is essential to unlock its full potential for clinical and industrial use.