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In recent years, there has been increased efforts on the development of innovative cellulose-based materials such as cellulose nanocrystals (CNCs)Cellulose Nanocrystals (CNC), cellulose nanofibrils (CNFs)Cellulose Nanofibrils (CNF), and bacterial cellulose (BC)Bacterial Cellulose (BC), among others, gaining much interest as potential sustainable platforms for the incorporation of antibacterial agents toward biomedical applicationsBiomedical applications. These materials are obtained from the highly abundant natural cellulose and showcased enhanced biocompatibilityBiocompatibility, mechanical strength, and chemical surface functionalizationSurface functionalization. These properties facilitate the incorporation of antimicrobial active ingredients such as metal ions (e.g., copper, silver, and zinc), nanoparticles (e.g. silver and gold), or molecular compounds (e.g., antibiotics, antiseptics, and antifungals). This study investigates the recently reported applications ofFunctionalized cellulose functionalized cellulose-based materials loaded with antimicrobial actives ingredients, as alternative strategies against bacterial infections. These cellulose materialsCellulose materials are suitable for a broad scope of applications, ranging from biomedical relevant with wound dressings, medical coatingsAntibacterial coatings, all the way to healthcare with water purification and pathogen-resistantPathogen-resistant materials packaging. Furthermore, the versatile surface modification and green synthesesGreen syntheses associated with cellulose-based materials as delivery systems support their appeal as sustainable antimicrobial strategy. Collectively, these wide range of cellulose materialsCellulose materials showcased effective antimicrobial activity and increased stability, while preserving great biocompatibilityBiocompatibility with living tissues. Thus, corroborating the potential suitability and applicability of cellulose-based materials as effective antibacterial treatment for applications in healthcare and biomedical sectors. Herein, this review summarizes recently developed cellulose-based antibacterial materials, highlighting their synthesis methods, reported results, and their relevancy to multiple antimicrobial applications within the biomedical sector.

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Cellulose-Based Material as Antibacterial Agent

  • 章节

  • 发表日期：

    2025年

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  • Bhanu Sharma,
  • Preeti Maiti,
  • Edwin Davidson,
  • Cecilia Ezeanya,
  • Jorge Pereira,
  • Swadeshmukul Santra

摘要

In recent years, there has been increased efforts on the development of innovative cellulose-based materials such as cellulose nanocrystals (CNCs)Cellulose Nanocrystals (CNC), cellulose nanofibrils (CNFs)Cellulose Nanofibrils (CNF), and bacterial cellulose (BC)Bacterial Cellulose (BC), among others, gaining much interest as potential sustainable platforms for the incorporation of antibacterial agents toward biomedical applicationsBiomedical applications. These materials are obtained from the highly abundant natural cellulose and showcased enhanced biocompatibilityBiocompatibility, mechanical strength, and chemical surface functionalizationSurface functionalization. These properties facilitate the incorporation of antimicrobial active ingredients such as metal ions (e.g., copper, silver, and zinc), nanoparticles (e.g. silver and gold), or molecular compounds (e.g., antibiotics, antiseptics, and antifungals). This study investigates the recently reported applications ofFunctionalized cellulose functionalized cellulose-based materials loaded with antimicrobial actives ingredients, as alternative strategies against bacterial infections. These cellulose materialsCellulose materials are suitable for a broad scope of applications, ranging from biomedical relevant with wound dressings, medical coatingsAntibacterial coatings, all the way to healthcare with water purification and pathogen-resistantPathogen-resistant materials packaging. Furthermore, the versatile surface modification and green synthesesGreen syntheses associated with cellulose-based materials as delivery systems support their appeal as sustainable antimicrobial strategy. Collectively, these wide range of cellulose materialsCellulose materials showcased effective antimicrobial activity and increased stability, while preserving great biocompatibilityBiocompatibility with living tissues. Thus, corroborating the potential suitability and applicability of cellulose-based materials as effective antibacterial treatment for applications in healthcare and biomedical sectors. Herein, this review summarizes recently developed cellulose-based antibacterial materials, highlighting their synthesis methods, reported results, and their relevancy to multiple antimicrobial applications within the biomedical sector.