Progressive collapse refers to the total or partial failure of a structure due to an initial localized failure that propagates throughout the system. Several catastrophic incidents of progressive collapse have occurred in recent decades. Various factors influence the ability of a structure to prevent the spread of local failure, one of which is its geometric configuration. This study examines the impact of geometric configuration on the progressive collapse behavior of RC framed systems. A global nonlinear static pushdown analysis was conducted on 3D frame models to evaluate their structural robustness, considering two column-removal scenarios to simulate the extreme loading conditions. The results indicate that geometric configuration significantly affects the load redistribution ability of RC framed systems. Additionally, the study emphasizes the role of the number of bays and storeys in enhancing the resistance to progressive collapse. The findings offer valuable insights that could contribute to improving the progressive collapse design of RC frame structures.