The paper presents the concept of a “cyber-physical nurse” from a feasibility perspective for wider inclusion in healthcare, in particular in relation to empathic communication with the patient. The results of a pilot study on user perception of two robotic and one human faces are presented and discussed in this context. Users attributed positive features to neutral agents’ facial expressions, but not negative, which increases the feasibility of introducing social robots in healthcare. Some guidelines for cyber-physical nurse design are discussed, addressing challenges to its possible implementation in hospitals, rehabilitation centres, and home care settings.