Due to the COVID-19 pandemic, most companies have learned to shift to remote working. Although traditionally considered as the more flexible arrangement, remote working had been linked to the experience of stress, discomfort, and burnout. This study explores the different factors that could potentially impact one’s experience of burnout. To achieve this, an online survey was conducted with 160 Filipino respondents who are working either in a fully remote or in a hybrid arrangement. Findings revealed that among all the factors considered, personality is the largest factor to the remote worker’s frequency of experiencing emotional exhaustion, personal accomplishment, and depersonalization. Moreover, having a managerial role was found to be a significant factor contributing to depersonalization while high tenure was positively correlated to emotional exhaustion. Further research can be extended to the study of burnout intervention programs that integrate one’s personality and which can be implemented even for workers in partial or fully remote work arrangements.