In the scenario of the inclusive transition of present society, the concept of Inclusive Living Communities (ILCs) promotes socially inclusive interventions at different scales, from services to products and communication systems. The goal is to mitigate social inequalities by promoting new forms of wellbeing. Accordingly, citizens benefit from a novel cultural framework and innovative visions that are relevant for Design studies. Due to the scale and the magnitude of impacts expected by interventions within ILCs, the use of a System Design for Social Inclusion (SDSI) framework is proposed as a valuable cultural reference capable to orient the development of inclusive systems of solutions, intended as mixes of services, artefacts, and communication systems resulting from codesigned processes, which help policymakers to make in place strategic inclusive visions for all citizens. This work discusses the application of the SDSI framework in the cultural context of ILCs. Four goal-oriented inclusive design strategies are synthetically presented against emerging trends connecting Inclusive Design and the ILCs phenomenon to offer themed explorations on different aspects that are considered as relevant.