The increasing global population necessitates a heightened demand for food and energy, consequently prompting the intensification of agricultural production. This intensification often requires a greater use of fertilizers and pesticides, which may lead to progressive soil and groundwater contamination. How to stop this snowball effect? One potential solution to mitigate these challenges lies in nanotechnology, which could enhance plant fertilization efficiency through engineered nanoparticles (ENPs). Due to their nanoscale size, these particles exhibit unique and advantageous properties, leading to the exploration of new applications across various economic sectors, including agriculture. In the realm of fertilizers, ENPs present promising opportunities as their small size allows them to penetrate the cell wall barrier compared to larger particles more easily. Moreover, metal-based ENPs are characterized by gradual solubility, which enables them to release nutrients over an extended period, unlike traditional fertilizers that release their entire ion pool quickly. Despite the long-discussed fertilizing potential of ENPs since the advent of nanotechnology, there remain numerous uncertainties regarding the conditions of their application and their superiority over conventional fertilizers. This chapter conducts a comparative analysis of existing studies on the use of ENPs as micronutrient fertilizers for plants. The analysis of collected data aims to guide future research, potentially resulting in the optimized application of nano-agrochemicals.