The realm of reproductive mental health, a critical yet often neglected dimension of well-being, assumes a particularly complex and urgent character within the context of marginalised women in South Asia. Such women face a range of reproductive mental health disorders, at different phases of the reproductive period, ranging from menarche to menopause, through the pregnancy/perinatal period, with psychological distress linked to reproductive experiences including abortion and contraceptive use. Studies on marginalised women in South Asian countries like India, Pakistan, and Nepal have shown varying prevalence across studies and regions, ranging from around 15% to 35% which is higher than the global average. Financial stress, ethnic minority, lack of social support, domestic violence, and cultural dogma make them particularly vulnerable to stress, isolation, and discrimination during this period. Women’s vulnerability to mental illness including suicide in the region is deeply influenced by sociocultural factors, including early marriage and dowry pressures, expectations to bear children and associated societal demands, and gender-based violence (GBV), including domestic abuse. There is a need for a comprehensive approach to develop policies to address perinatal mental health needs, considering the high disease burden and several sociocultural barriers amplified in marginalised women.