The rise of postharvest nanobiotechnology that enhances the care and usage of agricultural products results from the convergence of nanobiotechnology’s advancements in developing real-time smart detection devices and intelligent materials. It also covers how modern information technology aids in achieving higher quality agricultural products through automatic freshness and environmental condition monitoring. This part also explains the possibility of real-time monitoring of food quality and safety during transport and sales. In the case studying the application of nanobiotechnology, great care is taken to avoid violations of ethical regulations as it pertains to the food systems. This chapter has provided evidence how document authentic nanobiotechnology could transform everything postharvest in readiness, authenticity, shelf life, and ultimately, safety to the consumer.