One of the earliest records of photosensitivity can be traced back to the sixteenth century when sunlight exposure followed by buckwheat intake induced a skin response in animals. In the eighteenth century, people in Sicily and Naples reported that white sheep developed severe skin reactions after consuming hypericum, such effects were not observed in black sheep [1].

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History of Photodynamic Therapy

  • Zhi Cao,
  • Hongwei Wang,
  • Bo Wang,
  • Xiuli Wang

摘要

One of the earliest records of photosensitivity can be traced back to the sixteenth century when sunlight exposure followed by buckwheat intake induced a skin response in animals. In the eighteenth century, people in Sicily and Naples reported that white sheep developed severe skin reactions after consuming hypericum, such effects were not observed in black sheep [1].