The metal foam (MF) and nanofluid combination receives a considerable interest now a days for the intensification of heat transfer and designing a suitable thermal device. In view of this, the present work concentrates on finding out the exergy analysis through (MF) filled asymmetrical heated channel. The domain of interest of the present examination comprises of a channel (horizontal) with top wall heated from the aluminum plate heater assemblage. Water and Al2O3 nanofluid flows through the channel and takes away the heat from plate and velocity of fluid ranges from 0.02 to 0.15 m/s. Pore density of 20 and porosity of 0.918 MF is placed below the aluminum plate in order improve the rate of heat transfer. The flow physics through the MF is captured with the help of DEF flow (Darcy Extended Forchhiemer) model and LTE model (Local thermal equilibrium) is preferred for predicting the thermal physics. The method adopted in the present analysis is authenticated by comparing with literature outcomes. The results such as pressure loss, Nusselt number, derived and lost exergy Nusselt number are presented and discussed. The result proves that the nanofluid performs the best in terms of exergy compared to water fluid.