Pile foundations play a crucial role in providing stability to various structures, including transmission towers, bridge abutments, open-type berthing structures, and high-rise buildings, especially when they are constructed on slopes. However, the lateral load capacity of pile foundations can be significantly reduced under sloped conditions due to the loads induced by wind, wave currents, traffic, and seismic events. The stability of the structure becomes a concern, particularly depending on the foundation’s proximity to the slope crest. This study aimed to comprehensively investigate the impact of slope angle and the distance of both single piles and pile groups from the slope crest on their lateral load carrying capacity. The research utilized a combination of experimental and analytical approaches. In the laboratory, scaled experimental model tests were conducted using a test tank of size 1.2 m × 0.6 m × 0.8 m for three distinct ground conditions of (i) flat ground, (ii) steep slope (1 V:1.5H), and (iii) moderate slope (1 V:2.5H). The experimental results revealed a clear trend in which the lateral load capacity of the piles increased with greater edge distances and with a transition from steep to moderate and then flat ground conditions. The findings have implications for optimizing the design and placement of pile foundations in sloped conditions. The percentage variation in lateral load capacity found to be within the negligible range of less than 5% for the cases of 20D edge distance on a 1 V:1.5H slope and 15D edge distance on a 1 V:2.5H slope when compared with horizontal ground conditions.