In 1952, a mysterious disease broke out in Minamata, a small fishing village in Kyushu, Japan. Waterfowl flying in the sky suddenly fell to the ground, and domestic cats began spinning uncontrollably, foaming at the mouth. This bizarre phenomenon appeared throughout the village. A year later, the disease also affected the local residents. The main symptoms included paralysis of the hands and feet, pain and chills, headaches, visual impairment, motor dysfunction, and speech disorders. In severe cases, intense pain and paralysis led to death, and infants were born either deformed or stillborn.