A series of brain tumor deaths occurred among faculty and students at San Diego State University in California, USA. The deaths, which began in 1993, increased further during the 2000s. Notably, all seven deceased staff members (1 in 1993, 4 in 2008, 1 in 2010, 1 in 2013) and three students (1 in 2008, 1 in 2011, 1 in 2012) had worked in or near Room 131 of Nasatir Hall or adjacent campus buildings. This mystery came to public attention when Virginia Faver, the mother of Richard Faver, a political science graduate student who died in 2008, publicly investigated and traced the cause and progression of her son’s brain tumor.