The adverse susceptibility of oilseed cultivars to prolonged edaphic saturation, inundation events, and persistent waterlogging and flooding significantly hinders progress toward global agricultural pillars. These abiotic stressors produce significant perturbations in pathways for nutrient acquisition, metabolic homeostasis, and physiological functionality, leading to substantial yield decrements. The development of agricultural biotechnology stemming from the use of biostimulatory compounds on contemporary crops, such as humic derivatives, proteolytic hydrolysates, beneficial microbial consortia, and algal extracts, has already shown efficacy in counteracting the devastating consequences of excessive hydrological conditions. This chapter aims to quantitatively explain the resilience threshold of oilseed crops to the effects of waterlogging and flooding stress regimes. These bioactive compounds are supported by empirical evidence that they promote rhizospheric oxygenation processes, facilitate nutrient assimilation kinetics, and augment antioxidative defense mechanisms to improve the growth of plants in harsh conditions. Basic biochemical modulation of this kind substantially improves crop adaptability to such hydrological stresses. Remarkably, the morphophysiological development indices, agronomic yield components’ parameters, and stress tolerance parameters are well augmented by amino acid constituents, rhizospheric microbial inoculants, and algal derivatives in affected plant systems. The existing comprehensive analysis integrates extant scientific paradigms harmoniously to identify the important lacunae of knowledge and a means to successfully counter waterlogging-induced physiological perturbation in a complex agronomic and biostimulant management situation. Despite the limitations, the research outcomes emphasized the importance of continuing with investigative efforts to ascertain the best strategies for executing application methods, dosage regimens, and time frames in biostimulant application for the sustainability of agricultural practice for an improvement in the food security maturities in hydrologically vulnerable agroecosystems.