The research informatization infrastructure platform serves as an essential foundation for contemporary scientific research and a critical indicator of national scientific and technological innovation capacity. Nations globally emphasize the construction and investment in research informatization infrastructure platforms, resulting in numerous significant accomplishments. The swift advancement of information technology and industry has prompted a transformation in the research informatization infrastructure platform. The novel research informatization infrastructure platform aims to enhance the support for scientific research by prioritizing technological advancements in areas such as cross-domain global intelligent scheduling, massive data storage and efficient data collection, intelligent computility, domain-specific large artificial intelligence (AI) models, and AI-oriented high-quality scientific data, among others. The construction and application of the platform will realize transparent coherence between the physical world and the digital world, accelerate the realization of critical scientific and technological breakthroughs, and push forward the shift of intelligent scientific research paradigm.