Artificial intelligence (AI), a powerful tool that imitates human thinking using computers, has become a game-changer in our daily lives. AI is transforming medical research and healthcare, showing impressive results in precision medicine and personalised healthcare. With the increasing amount of data in the field, traditional analysis methods fall short. This transformation is especially notable in biomarker discovery and disease diagnosis, with a growing need for more accurate and efficient medical solutions. AI is crucial in deciphering complex patterns within massive datasets, finding subtle connections, and identifying biomarkers—key indicators of normal and abnormal biological processes. This, in turn, speeds up the early detection of diseases and improves our ability to predict outcomes. Integrating AI and machine learning algorithms enhances the precision of diagnoses, reduces the time it takes to diagnose, and ultimately enhances how patients fare. This chapter explores the practical challenges and opportunities of incorporating AI into biomarker discovery to provide insights into how AI is making a real impact in the world, transforming how we discover biomarkers, diagnose diseases, and contribute to better healthcare outcomes. Through the influence of AI on medical research, we aim to give a clear picture of how AI is changing the landscape of biomarker discoveries, revolutionising disease diagnosis, and ultimately leading to improved healthcare results.