This chapter focuses on understanding marriage from a mental health perspective and its evolving narrative in the context of South Asia. Marriage’s salutary benefit is determined by the perceived and actual social support and attachment with the partners. In this chapter, the authors have outlined critical aspects of marriage and mental health, including differences between South Asia and Western societies, experience of marriage in people with mental illness and their partners, including caregiver burden. Here, we have also discussed the impact of age on marriage and mental health outcomes, intimate partner violence, perceived social support, gender differences concerning the marriage and mental health. Towards, the later part of the chapter, tools to measure dimensions of marriage and relationships, therapeutic management of marital issues, legal aspects of marriage and mental health in South Asia, and current research gap which needs further exploration were also highlighted. Essential research has been included to give a comprehensive glimpse into marriage and mental health while underlining the areas that need more in-depth understanding and empirical evidence.