South Asia known for its cultural diversity, is recognized as the most densely populated region in the world. The majority of its countries fall into the categories of low- and middle-income, known as LAMICs. Within this richly varied cultural landscape, deeply ingrained beliefs and practices significantly influence the understanding and manifestation of psychopathology. The unique cultural nuances in South Asia give rise to specific forms of psychological distress, which may evolve in different ways across different communities. These forms of psychopathology can emerge as isolated instances or, at times, manifest in larger epidemic patterns, reflecting the intricate interplay between culture and mental health. This chapter discusses about the culture-bound syndromes that are prevalent in South Asia, exploring how these conditions are shaped by and interwoven with local customs, traditions, and societal norms.