Recent Progress in Hydroxyapatite-Based Composite Coatings for Biomedical Applications
摘要
Bone tissue is like a blend of tiny building blocks, made up of both organic and inorganic materials. The organic part is mainly collagen, while the inorganic part is similar to a ceramic called hydroxyapatite (HA), found in vertebrate bones. However, HA, while similar to bone mineral, is not strong enough on its own for bone repairs. To address this, researchers mix HA with different polymers and strengthening agents to create composite coatings. These composites can help to improve the mechanical properties of the material, making it more suitable for bone repairs. Recent research focuses on combining HA with various polymers and cross-linkers to create better materials for bone regeneration. These composites are generally found to be compatible with the body. However, the results from human trials are still debated. In essence, this review discusses the latest advancements in HA-based composite coatings for bone repair, including the different materials used, how they are made and their performance in laboratory and clinical settings. It aims to provide a helpful overview for researchers exploring these materials for medical applications.